Microbial transformation of macrocyclic trichothecenes.

نویسندگان

  • G Pavanasasivam
  • B B Jarvis
چکیده

A resting culture of Rhizopus arrhizus (ATCC 11145) transformed verrucarin A into 16-hydroxyverrucarin A, whereas R. arrhizus transformed verrucarin B into a mixture of 16-hydroxyverrucarin B and 3'-hydroxyverrucarin A. Relative to verrucarins A and B, the 16-hydroxy derivatives showed marked increases in activity, as tested in vivo against P388 mouse leukemia.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 46 2  شماره 

صفحات  -

تاریخ انتشار 1983